FOXN4 Antikörper (AA 89-194)

Produktnummer ABIN7153076

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FOXN4 in ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FOXN4 Antikörper (AA 89-194) (ABIN7153076)

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXN4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-FOXN4 Antikörper

Bindungsspezifität: AA 89-194

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Forkhead box protein N4 protein (89-194AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FOXN4

Target: FOXN4 (Forkhead Box N4 (FOXN4))

Andere Bezeichnung: FOXN4

Hintergrund:

Background: Transcription factor essential for neural and some non-neural tissues development, such as retina and lung respectively. Binds to an 11-bp consensus sequence containing the invariant tetranucleotide 5\'-ACGC-3\'. During development of the central nervous system, is required to specify the amacrine and horizontal cell fates from multipotent retinal progenitors while suppressing the alternative photoreceptor cell fates through activating DLL4-NOTCH signaling. Also acts synergistically with ASCL1/MASH1 to activate DLL4-NOTCH signaling and drive commitment of p2 progenitors to the V2b interneuron fates during spinal cord neurogenesis. In development of non-neural tissues, plays an essential role in the specification of the atrioventricular canal and is indirectly required for patterning the distal airway during lung development (By similarity).

Aliases: FOXN4Forkhead box protein N4 antibody

UniProt: Q96NZ1