FOLR1 Antikörper (AA 25-234)
Kurzübersicht für FOLR1 Antikörper (AA 25-234) (ABIN7152986)
Target
Alle FOLR1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 25-234
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Folate receptor alpha protein (25-234AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000, IF:1:200-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FOLR1 (Folate Receptor 1 (Adult) (FOLR1))
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Andere Bezeichnung
- FOLR1
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Hintergrund
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Background: Binds to folate and reduced folic acid derivatives and mediates delivery of 5-methyltetrahydrofolate and folate analogs into the interior of cells. Has high affinity for folate and folic acid analogs at neutral pH . Exposure to slightly acidic pH after receptor endocytosis triggers a conformation change that strongly reduces its affinity for folates and mediates their release. Required for normal embryonic development and normal cell proliferation.
Aliases: adult antibody, Adult folate binding protein antibody, Adult folate-binding protein antibody, FBP antibody, Folate Binding Protein antibody, Folate Receptor 1 Adult antibody, Folate receptor 1 antibody, Folate Receptor 1 Precursor antibody, Folate receptor adult antibody, Folate receptor alpha antibody, Folate receptor antibody, FOLR antibody, FOLR1 antibody, FOLR1_HUMAN antibody, FR alpha antibody, FR-alpha antibody, FRalpha antibody, KB cells FBP antibody, MOV18 antibody, Ovarian cancer associated antigen antibody, Ovarian tumor associated antigen antibody, Ovarian tumor associated antigen MOv18 antibody, Ovarian tumor-associated antigen MOv18 antibody
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UniProt
- P15328
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Pathways
- Dicarboxylic Acid Transport
Target
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