FAIM3 Antikörper (AA 18-251)
Kurzübersicht für FAIM3 Antikörper (AA 18-251) (ABIN7152579)
Target
Alle FAIM3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 18-251
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Fas apoptotic inhibitory molecule 3 protein (18-251AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- FAIM3 (Fas Apoptotic Inhibitory Molecule 3 (FAIM3))
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Andere Bezeichnung
- FCMR
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Hintergrund
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Background: May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation.
Aliases: Faim3 antibody, FAIM3_HUMAN antibody, Fas apoptotic inhibitory molecule 3 antibody, Fc fragment of IgM receptor antibody, Fc mu receptor antibody, FCMR antibody, IgM Fc receptor antibody, Immunoglobulin mu Fc receptor antibody, Regulator of Fas induced apoptosis antibody, Regulator of Fas-induced apoptosis Toso antibody, TOSO antibody
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UniProt
- O60667
Target
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