FBXL21 Antikörper (AA 78-137)

Produktnummer ABIN7152480

Der Kaninchen Polyklonal Anti-FBXL21-Antikörper wurde für ELISA, WB, IHC und IF validiert. Er ist geeignet, FBXL21 in Proben von Human zu detektieren.

Kurzübersicht für FBXL21 Antikörper (AA 78-137) (ABIN7152480)

Target: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXL21 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-FBXL21 Antikörper

Bindungsspezifität: AA 78-137

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human F-box/LRR-repeat protein 21 protein (78-137AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FBXL21

Target: FBXL21 (F-Box and Leucine-Rich Repeat Protein 21 (FBXL21))

Andere Bezeichnung: FBXL21

Hintergrund:

Background: Substrate-recognition component of the SCF(FBXL21) E3 ubiquitin ligase complex involved in circadian rhythm function. Plays a key role in the maintenance of both the speed and the robustness of the circadian clock oscillation. The SCF(FBXL21) complex mainly acts in the cytosol and mediates ubiquitination of CRY proteins (CRY1 and CRY2), leading to CRY proteins stabilization. The SCF(FBXL21) complex counteracts the activity of the SCF(FBXL3) complex and protects CRY proteins from degradation. Involved in the hypothalamic suprachiasmatic nucleus (SCN) clock regulating temporal organization of the daily activities (By similarity).

Aliases: F box and leucine rich repeat protein 21 antibody, F box and leucine rich repeat protein 3 pseudogene antibody, F box and leucine rich repeat protein 3B antibody, F box protein Fbl3b antibody, F box/LRR repeat protein 21 antibody, F box/LRR repeat protein 3B antibody, F-box and leucine-rich repeat protein 21 antibody, F-box and leucine-rich repeat protein 3B antibody, F-box/LRR-repeat protein 21 antibody, F-box/LRR-repeat protein 3B antibody, Fbl 21 antibody, FBL 3 antibody, FBL 3B antibody, Fbl21 antibody, FBL3 antibody, FBL3B antibody, FBXL 21 antibody, FBXL 3B antibody, FBXL 3P antibody, Fbxl21 antibody, FBXL3B antibody, FBXL3P antibody, FXL21_HUMAN antibody, MGC120237 antibody

UniProt: Q9UKT6

Pathways: Photoperiodism