F-Box Protein 3 Antikörper (AA 276-376)
Kurzübersicht für F-Box Protein 3 Antikörper (AA 276-376) (ABIN7152425)
Target
Alle F-Box Protein 3 (FBXO3) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 276-376
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Kreuzreaktivität
- Human, Maus
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human F-box only protein 3 protein (276-376AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:200-1:5000, IHC:1:20-1:200, IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- F-Box Protein 3 (FBXO3)
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Andere Bezeichnung
- FBXO3
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Hintergrund
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Background: Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Aliases: F Box G - Domain 3 antibody, F box only protein 3 antibody, F box protein 3 antibody, F box protein FBX3 antibody, F-box only protein 3 antibody, FBA antibody, FBX3 antibody, FBX3_HUMAN antibody, FBXO3 antibody
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UniProt
- Q9UK99
Target
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