FBXO2 Antikörper (AA 1-296)

Produktnummer ABIN7152410

Produktdetails anti-FBXO2 Antikörper

Target: FBXO2 (F-Box Protein 2 (FBXO2))

Bindungsspezifität: AA 1-296

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXO2 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human F-box only protein 2 protein (1-296AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FBXO2

Target: FBXO2 (F-Box Protein 2 (FBXO2))

Andere Bezeichnung: FBXO2 (FBXO2 Produkte)

Synonyme: FBG1 antikoerper, FBX2 antikoerper, Fbs1 antikoerper, NFB42 antikoerper, OCP1 antikoerper, Fbs2 antikoerper, Prpl4 antikoerper, F-box protein 2 antikoerper, FBXO2 antikoerper, Fbxo2 antikoerper

Hintergrund:

Background: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).

Aliases: F box gene 1 antibody, F box only protein 2 antibody, F box protein 2 antibody, F box protein only 2 antibody, F-box only protein 2 antibody, FBG 1 antibody, FBG1 antibody, Fbs 1 antibody, Fbs1 antibody, Fbs2 antibody, FBX 2 antibody, FBX2 antibody, FBX2_HUMAN antibody, FBXO 2 antibody, FBXO2 antibody, Neural F box protein NFB42 antibody, Neural F-box protein, 42-KD, rat, homolog of antibody, NFB 42 antibody, NFB42 antibody, OCP1 antibody, organ of Corti protein 1 antibody, Prpl4 antibody

UniProt: Q9UK22