F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1184-1295) Antikörper
Kurzübersicht für F-Actin-Uncapping Protein LRRC16A (CARMIL1) (AA 1184-1295) Antikörper (ABIN7152382)
Target
Reaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1184-1295
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Verwendungszweck
- CARMIL1 Antibody
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Aufreinigung
- Protein G purified
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Reinheit
- >95 %
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Immunogen
- Recombinant Human F-actin-uncapping protein LRRC16A protein (1184-1295AA)
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- F-Actin-Uncapping Protein LRRC16A (CARMIL1)
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Andere Bezeichnung
- CARMIL1
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Hintergrund
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Background: Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments (PubMed:16054028). Plays a role in lamellipodial protrusion formations and cell migration (PubMed:19846667).
Aliases: Acan 125 antibody, Capping protein, Arp2/3, and myosin I linker antibody, CARMIL homolog antibody, leucine rich repeat containing 16 antibody, Leucine-rich repeat-containing protein 16A antibody, LR16A_HUMAN antibody, Lrrc16 protein antibody, LRRC16A antibody, p116 antibody
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UniProt
- Q5VZK9
Target
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