FAM20C Antikörper (AA 107-224) (HRP)

Produktnummer ABIN7152341

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch FAM20C in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FAM20C Antikörper (AA 107-224) (HRP) (ABIN7152341)

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAM20C Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-FAM20C Antikörper (HRP)

Bindungsspezifität: AA 107-224

Verwendungszweck: FAM20C Antibody, HRP conjugated

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Extracellular serine/threonine protein kinase FAM20C protein (107-224AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu FAM20C

Target: FAM20C (Family with Sequence Similarity 20, Member C (FAM20C))

Andere Bezeichnung: FAM20C

Hintergrund:

Background: Golgi serine/threonine protein kinase that phosphorylates secretory pathway proteins within Ser-x-Glu/pSer motifs and plays a key role in biomineralization of bones and teeth (PubMed:22582013, PubMed:23754375, PubMed:25789606). Constitutes the main protein kinase for extracellular proteins, generating the majority of the extracellular phosphoproteome (PubMed:26091039). Mainly phosphorylates proteins within the Ser-x-Glu/pSer motif, but also displays a broader substrate specificity (PubMed:26091039). Phosphorylates casein as well as a number of proteins involved in biomineralization such as AMELX, AMTN, ENAM and SPP1 (PubMed:22582013, PubMed:25789606). In addition to its role in biomineralization, also plays a role in lipid homeostasis, wound healing and cell migration and adhesion (PubMed:26091039).

Aliases: C76981 antibody, Dentin matrix protein 4 antibody, DKFZp547C074 antibody, DMP-4 antibody, DMP4 antibody, DMP4_HUMAN antibody, Extracellular serine/threonine protein kinase Fam20C antibody, Fam20c antibody, Family with sequence similarity 20 member C antibody, GEF CK antibody, Golgi enriched fraction casein kinase antibody, Protein FAM20C antibody, RNS antibody

UniProt: Q8IXL6