EIF6 Antikörper (AA 1-245)

Produktnummer ABIN7152221

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch EIF6 in IHC, ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für EIF6 Antikörper (AA 1-245) (ABIN7152221)

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF6 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-EIF6 Antikörper

Bindungsspezifität: AA 1-245

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Eukaryotic translation initiation factor 6 protein (1-245AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu EIF6

Target: EIF6 (Eukaryotic Translation Initiation Factor 6 (EIF6))

Andere Bezeichnung: EIF6

Hintergrund:

Background: Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity.

Aliases: b(2)gcn antibody, B(2)GCN homolog antibody, B4 integrin interactor antibody, Binding protein of beta-4 integrin antibody, CAB antibody, eIF-6 antibody, EIF3A antibody, EIF6 antibody, Eukaryotic translation initiation factor 3A antibody, Eukaryotic translation initiation factor 6 antibody, IF6_HUMAN antibody, Integrin beta 4 binding protein antibody, ITGB4BP antibody, OK/SW-cl.27 antibody, p27 beta 4 integrin binding protein antibody, p27(BBP) antibody, p27BBP antibody, RP4-614O4.1 antibody

UniProt: P56537

Pathways: Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly