Elf4 Antikörper (AA 1-200)

Produktnummer ABIN7152098

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Elf4 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Elf4 Antikörper (AA 1-200) (ABIN7152098)

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Elf4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Elf4 Antikörper

Bindungsspezifität: AA 1-200

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human ETS-related transcription factor Elf-4 protein (1-200AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Elf4

Target: Elf4 (E74 like ETS transcription factor 4 (Elf4))

Andere Bezeichnung: ELF4

Hintergrund:

Background: Transcriptional activator that binds to DNA sequences containing the consensus 5\\\'-WGGA-3\\\'. Transactivates promoters of the hematopoietic growth factor genes CSF2, IL3, IL8, and of the bovine lysozyme gene. Acts synergistically with RUNX1 to transactivate the IL3 promoter (By similarity). Also transactivates the PRF1 promoter in natural killer (NK) cells. Plays a role in the development and function of NK and NK T-cells and in innate immunity. Controls the proliferation and homing of CD8+ T-cells via the Kruppel-like factors KLF4 and KLF2 (By similarity). Controls cell senescence in a p53-dependent manner. Can also promote cellular transformation through inhibition of the p16 pathway.

Aliases: E74-like factor 4 antibody, ELF4 antibody, ELF4_HUMAN antibody, ELFR antibody, ETS-related transcription factor Elf-4 antibody, ETS-related transcription factor Elf4 antibody, MEF antibody, Myeloid Elf-1-like factor antibody, Myeloid Elf1-like factor antibody

UniProt: Q99607

Pathways: Positive Regulation of Endopeptidase Activity