TRIM25 Antikörper (AA 81-272)

Produktnummer ABIN7151322

Der Kaninchen Polyklonal Anti-TRIM25-Antikörper wurde für WB, ELISA, IHC und IF validiert. Er ist geeignet, TRIM25 in Proben von Human zu detektieren.

Kurzübersicht für TRIM25 Antikörper (AA 81-272) (ABIN7151322)

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM25 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TRIM25 Antikörper

Bindungsspezifität: AA 81-272

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin/ISG15 ligase TRIM25 protein (81-272AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRIM25

Target: TRIM25 (Tripartite Motif Containing 25 (TRIM25))

Andere Bezeichnung: TRIM25

Hintergrund:

Background: Functions as a ubiquitin E3 ligase and as an ISG15 E3 ligase. Involved in innate immune defense against viruses by mediating ubiquitination of DDX58. Mediates \\\'Lys-63\\\'-linked polyubiquitination of the DDX58 N-terminal CARD-like region which is crucial for triggering the cytosolic signal transduction that leads to the production of interferons in response to viral infection. Promotes ISGylation of 14-3-3 sigma (SFN), an adapter protein implicated in the regulation of a large spectrum signaling pathway. Mediates estrogen action in various target organs. Mediates the ubiquitination and subsequent proteasomal degradation of ZFHX3 (PubMed:22452784).

Aliases: E3 ubiquitin/ISG15 ligase TRIM25 antibody, EFP antibody, Estrogen responsive finger protein antibody, Estrogen-responsive finger protein antibody, RING finger protein 147 antibody, RNF 147 antibody, RNF147 antibody, TRI25 antibody, TRI25_HUMAN antibody, TRIM 25 antibody, Trim25 antibody, Tripartite motif containing 25 antibody, Tripartite motif containing protein 25 antibody, Tripartite motif protein TRIM25 antibody, Tripartite motif-containing protein 25 antibody, Tripartite motifcontaining25 antibody, Ubiquitin/ISG15-conjugating enzyme TRIM25 antibody, Z147 antibody, Zinc finger protein 147 (estrogen responsive finger protein) antibody, Zinc finger protein 147 antibody, Zinc finger protein-147 antibody, ZNF 147 antibody, ZNF147 antibody

UniProt: Q14258