UBR2 Antikörper (AA 101-439) (HRP)

Produktnummer ABIN7151300

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch UBR2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für UBR2 Antikörper (AA 101-439) (HRP) (ABIN7151300)

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UBR2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-UBR2 Antikörper (HRP)

Bindungsspezifität: AA 101-439

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase UBR2 protein (101-439AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu UBR2

Target: UBR2 (Ubiquitin Protein Ligase E3 Component N-Recognin 2 (UBR2))

Andere Bezeichnung: UBR2

Hintergrund:

Background: E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Plays a critical role in chromatin inactivation and chromosome-wide transcriptional silencing during meiosis via ubiquitination of histone H2A. Binds leucine and is a negative regulator of the leucine-mTOR signaling pathway, thereby controlling cell growth.

Aliases: UBR2 antibody, C6orf133 antibody, KIAA0349 antibody, E3 ubiquitin-protein ligase UBR2 antibody, EC 2.3.2.27 antibody, N-recognin-2 antibody, RING-type E3 ubiquitin transferase UBR2 antibody, Ubiquitin-protein ligase E3-alpha-2 antibody, Ubiquitin-protein ligase E3-alpha-II antibody

UniProt: Q8IWV8