TRIM37 Antikörper (AA 301-600)

Produktnummer ABIN7151266

Dieses Anti-TRIM37-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von TRIM37 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für TRIM37 Antikörper (AA 301-600) (ABIN7151266)

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIM37 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-TRIM37 Antikörper

Bindungsspezifität: AA 301-600

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase TRIM37 protein (301-600AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TRIM37

Target: TRIM37 (Tripartite Motif Containing 37 (TRIM37))

Andere Bezeichnung: TRIM37

Hintergrund:

Background: E3 ubiquitin-protein ligase required to prevent centriole reduplication (PubMed:15885686, PubMed:23769972). Probably acts by ubiquitinating positive regulators of centriole reduplication (PubMed:23769972). Mediates monoubiquitination of \\\'Lys-119\\\' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression: associates with some Polycomb group (PcG) multiprotein PRC2-like complex and mediates repression of target genes (PubMed:25470042). Has anti-HIV activity (PubMed:24317724).

Aliases: E3 ubiquitin protein ligase TRIM37 antibody, E3 ubiquitin-protein ligase TRIM37 antibody, KIAA0898 antibody, MUL antibody, MUL protein antibody, Mulibrey nanism gene antibody, Mulibrey nanism protein antibody, POB 1 antibody, POB1 antibody, RING B box coiled coil protein antibody, TEF 3 antibody, TEF3 antibody, TRI37_HUMAN antibody, TRIM 37 antibody, Trim37 antibody, Tripartite motif containing 37 antibody, Tripartite motif containing 37 protein antibody, Tripartite motif containing protein 37 antibody, Tripartite motif-containing protein 37 antibody

UniProt: O94972