RNF6 Antikörper (AA 1-298)
Kurzübersicht für RNF6 Antikörper (AA 1-298) (ABIN7151204)
Target
Alle RNF6 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-298
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase RNF6 protein (1-298AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IF:1:50-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF6 (RING Finger Protein 6 (RNF6))
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Andere Bezeichnung
- RNF6
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Hintergrund
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Background: E3 ubiquitin-protein ligase mediating \'Lys-48\'-linked polyubiquitination of LIMK1 and its subsequent targeting to the proteasome for degradation. Negatively regulates axonal outgrowth through regulation of the LIMK1 turnover. Mediates \'Lys-6\' and \'Lys-27\'-linked polyubiquitination of AR/androgen receptor thereby modulating its transcriptional activity. May also bind DNA and function as a transcriptional regulator.
Aliases: E3 ubiquitin-protein ligase RNF6 antibody, Ring finger protein (C3H2C3 type) 6 antibody, Ring finger protein 6 antibody, RING H2 protein antibody, RING H2 protein RNF6 antibody, RNF 6 antibody, RNF6 antibody, RNF6_HUMAN antibody, SPG2 antibody
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UniProt
- Q9Y252
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Pathways
- Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Regulation of Cell Size
Target
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