MKRN1 Antikörper (AA 109-209)

Produktnummer ABIN7151059

Produktdetails anti-MKRN1 Antikörper

Target: MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))

Bindungsspezifität: AA 109-209

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MKRN1 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human E3 ubiquitin-protein ligase makorin-1 protein (109-209AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:500-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu MKRN1

Target: MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))

Andere Bezeichnung: MKRN1 (MKRN1 Produkte)

Synonyme: MKRN1 antikoerper, MGC84269 antikoerper, mkrn1 antikoerper, Makorin-1 antikoerper, RNF61 antikoerper, RFP antikoerper, makorin ring finger protein 1 antikoerper, E3 ubiquitin-protein ligase makorin-1 antikoerper, makorin ring finger protein 1 S homeolog antikoerper, makorin, ring finger protein, 1 antikoerper, MKRN1 antikoerper, LOC100393879 antikoerper, mkrn1.S antikoerper, Mkrn1 antikoerper

Hintergrund:

Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription.

Aliases: E3 ubiquitin-protein ligase makorin-1 antibody, FLJ21334 antibody, HGNC:7112 antibody, Makorin antibody, Makorin ring finger protein 1 antibody, MKRN 1 antibody, mkrn1 antibody, MKRN1_HUMAN antibody, OTTHUMP00000212117 antibody, OTTHUMP00000212118 antibody, OTTHUMP00000212121 antibody, OTTHUMP00000212124 antibody, Ring finger protein 1 antibody, RING finger protein 61 antibody, RNF61 antibody

UniProt: Q9UHC7

Pathways: Chromatin Binding