MKRN1 Antikörper (AA 109-209)
Kurzübersicht für MKRN1 Antikörper (AA 109-209) (ABIN7151059)
Target
Alle MKRN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 109-209
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase makorin-1 protein (109-209AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
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Andere Bezeichnung
- MKRN1
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Hintergrund
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Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription.
Aliases: E3 ubiquitin-protein ligase makorin-1 antibody, FLJ21334 antibody, HGNC:7112 antibody, Makorin antibody, Makorin ring finger protein 1 antibody, MKRN 1 antibody, mkrn1 antibody, MKRN1_HUMAN antibody, OTTHUMP00000212117 antibody, OTTHUMP00000212118 antibody, OTTHUMP00000212121 antibody, OTTHUMP00000212124 antibody, Ring finger protein 1 antibody, RING finger protein 61 antibody, RNF61 antibody
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UniProt
- Q9UHC7
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Pathways
- Chromatin Binding
Target
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