MKRN1 Antikörper (AA 109-209)
Kurzübersicht für MKRN1 Antikörper (AA 109-209) (ABIN7151059)
Target
Alle MKRN1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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    - 
                                            Bindungsspezifität
- AA 109-209
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                                            Kreuzreaktivität
- Human
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                                            Aufreinigung
- >95%, Protein G purified
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                                            Immunogen
- Recombinant Human E3 ubiquitin-protein ligase makorin-1 protein (109-209AA)
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                                            Isotyp
- IgG
 
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    - 
                                            Applikationshinweise
- Recommended dilution: IHC:1:500-1:1000,
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                                            Beschränkungen
- Nur für Forschungszwecke einsetzbar
 
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    - 
                                            Format
- Liquid
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                                            Buffer
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                        Preservative: 0.03 % Proclin 300
 Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
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                                            Konservierungsmittel
- ProClin
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                                            Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            Lagerung
- -20 °C,-80 °C
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                                            Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
 
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    - MKRN1 (Makorin Ring Finger Protein 1 (MKRN1))
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                                            Andere Bezeichnung
- MKRN1
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                                            Hintergrund
- 
                        Background: E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. These substrates include FILIP1, p53/TP53, CDKN1A and TERT. Keeps cells alive by suppressing p53/TP53 under normal conditions, but stimulates apoptosis by repressing CDKN1A under stress conditions. Acts as a negative regulator of telomerase. Has negative and positive effects on RNA polymerase II-dependent transcription. Aliases: E3 ubiquitin-protein ligase makorin-1 antibody, FLJ21334 antibody, HGNC:7112 antibody, Makorin antibody, Makorin ring finger protein 1 antibody, MKRN 1 antibody, mkrn1 antibody, MKRN1_HUMAN antibody, OTTHUMP00000212117 antibody, OTTHUMP00000212118 antibody, OTTHUMP00000212121 antibody, OTTHUMP00000212124 antibody, Ring finger protein 1 antibody, RING finger protein 61 antibody, RNF61 antibody 
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                                            UniProt
- Q9UHC7
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                                            Pathways
- Chromatin Binding
 Target
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