RNF20 Antikörper (AA 1-100)
Kurzübersicht für RNF20 Antikörper (AA 1-100) (ABIN7150987)
Target
Alle RNF20 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Verwendungszweck
- RNF20 Antibody
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Aufreinigung
- Protein G purified
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Reinheit
- >95 %
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase BRE1A protein (1-100AA)
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Isotyp
- IgG
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anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibody
RNF20 Reaktivität: Human WB, IF Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (Internal Region) antibodyRNF20 Reaktivität: Human, Maus WB, ELISA, IF, ICC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-260) antibodyRNF20 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) antibodyRNF20 Reaktivität: Human WB Wirt: Maus Monoclonal 4C6 unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 1-975) antibodyRNF20 Reaktivität: Human IP Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 177-276) antibodyRNF20 Reaktivität: Human WB, ELISA Wirt: Maus Monoclonal 1E4 unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 108-157) antibodyRNF20 Reaktivität: Human, Maus, Ratte, Hund, Kaninchen, Rind (Kuh), Pferd, Meerschweinchen, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (AA 576-625) antibodyRNF20 Reaktivität: Human, Maus, Hund, Rind (Kuh), Meerschweinchen, Schwein, Hamster, Affe WB Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 20 (RNF20) (N-Term) antibodyRNF20 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF20 (Ring Finger Protein 20 (RNF20))
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Andere Bezeichnung
- RNF20
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Hintergrund
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Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \\\'Lys-120\\\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \\\'Lys-4\\\' and \\\'Lys-79\\\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
Aliases: BRE1 A antibody, BRE1 antibody, BRE1 E3 ubiquitin ligase homolog antibody, BRE1-A antibody, BRE1A antibody, BRE1A_HUMAN antibody, E3 ubiquitin-protein ligase BRE1A antibody, hBRE1 antibody, Homolog of S. cerevisiae BRE1 antibody, RING finger protein 20 antibody, Ring finger protein 20 E3 ubiquitin protein ligase antibody, Rnf20 antibody
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UniProt
- Q5VTR2
Target
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