RNF2 Antikörper (AA 1-100)
Kurzübersicht für RNF2 Antikörper (AA 1-100) (ABIN7150987)
Target
Alle RNF2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-100
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human E3 ubiquitin-protein ligase BRE1A protein (1-100AA)
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Isotyp
- IgG
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anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibody
RNF2 Reaktivität: Human WB, ELISA, RNAi Wirt: Maus Monoclonal 6C2 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 1-336) antibodyRNF2 Reaktivität: Human WB, IHC, IF, IP, ChIP Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 192-290) antibodyRNF2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 2B6 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 164-223) antibodyRNF2 Reaktivität: Human WB, ELISA, IF Wirt: Maus Monoclonal 4C1 unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 Reaktivität: Human WB, ELISA, IHC, IF Wirt: Kaninchen Monoclonal 2H12 unconjugated Recombinant Antibody
anti-Ring Finger Protein 2 (RNF2) (Middle Region) antibodyRNF2 Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Zebrafisch (Danio rerio), Pferd, Kaninchen, Meerschweinchen WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 198-232) antibodyRNF2 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal RB52337 unconjugated
anti-Ring Finger Protein 2 (RNF2) (AA 165-199) antibodyRNF2 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB52402 unconjugated
anti-Ring Finger Protein 2 (RNF2) antibodyRNF2 Reaktivität: Human WB, IP Wirt: Kaninchen Monoclonal unconjugated
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- RNF2 (Ring Finger Protein 2 (RNF2))
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Andere Bezeichnung
- RNF2
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Hintergrund
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Background: Component of the RNF20/40 E3 ubiquitin-protein ligase complex that mediates monoubiquitination of \\\'Lys-120\\\' of histone H2B (H2BK120ub1). H2BK120ub1 gives a specific tag for epigenetic transcriptional activation and is also prerequisite for histone H3 \\\'Lys-4\\\' and \\\'Lys-79\\\' methylation (H3K4me and H3K79me, respectively). It thereby plays a central role inb histone code and gene regulation. The RNF20/40 complex forms a H2B ubiquitin ligase complex in cooperation with the E2 enzyme UBE2A or UBE2B, reports about the cooperation with UBE2E1/UBCH are contradictory. Required for transcriptional activation of Hox genes. Recruited to the MDM2 promoter, probably by being recruited by p53/TP53, and thereby acts as a transcriptional coactivator. Mediates the polyubiquitination of isoform 2 of PA2G4 in cancer cells leading to its proteasome-mediated degradation.
Aliases: BRE1 A antibody, BRE1 antibody, BRE1 E3 ubiquitin ligase homolog antibody, BRE1-A antibody, BRE1A antibody, BRE1A_HUMAN antibody, E3 ubiquitin-protein ligase BRE1A antibody, hBRE1 antibody, Homolog of S. cerevisiae BRE1 antibody, RING finger protein 20 antibody, Ring finger protein 20 E3 ubiquitin protein ligase antibody, Rnf20 antibody
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UniProt
- Q5VTR2
Target
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