CBX4 Antikörper (AA 401-560)

Produktnummer ABIN7150954

Dieses Anti-CBX4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CBX4 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für CBX4 Antikörper (AA 401-560) (ABIN7150954)

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CBX4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CBX4 Antikörper

Bindungsspezifität: AA 401-560

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity purified

Immunogen: Recombinant Human E3 SUMO-protein ligase CBX4 protein (401-560AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CBX4

Target: CBX4 (Chromobox Homolog 4 (CBX4))

Andere Bezeichnung: CBX4

Hintergrund:

Background: E3 SUMO-protein ligase which facilitates SUMO1 conjugation by UBE2I. Involved in the sumoylation of HNRNPK, a p53/TP53 transcriptional coactivator, hence indirectly regulates p53/TP53 transcriptional activation resulting in p21/CDKN1A expression. Monosumoylates ZNF131. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones, it mediates monoubiquitination of histone H2A \\\'Lys-119\\\', rendering chromatin heritably changed in its expressibility.

Aliases: CBX 4 antibody, CBX4 antibody, Cbx4 chromobox homolog 4 (Drosophila Pc class) antibody, CBX4_HUMAN antibody, Chromobox homolog 4 (Pc class homolog, Drosophila) antibody, Chromobox homolog 4 antibody, Chromobox protein homolog 4 antibody, E3 SUMO protein ligase CBX 4 antibody, E3 SUMO protein ligase CBX4 antibody, E3 SUMO-protein ligase CBX4 antibody, hPc 2 antibody, hPc2 antibody, NBP 16 antibody, NBP16 antibody, NS5ATP1 binding protein 16 antibody, Pc 2 antibody, Pc class 2 homolog antibody, Pc class homolog antibody, Pc class homolog Drosophila antibody, PC2 antibody, Polycomb 2 homolog antibody

UniProt: O00257