Dynamin 1-Like Antikörper (AA 496-710)

Produktnummer ABIN7150829

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch Dynamin 1-Like in WB, ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Dynamin 1-Like Antikörper (AA 496-710) (ABIN7150829)

Target: Dynamin 1-Like (DNM1L)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dynamin 1-Like Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-Dynamin 1-Like Antikörper

Bindungsspezifität: AA 496-710

Kreuzreaktivität: Human, Maus

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Dynamin-1-like protein (496-710AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Dynamin 1-Like

Target: Dynamin 1-Like (DNM1L)

Andere Bezeichnung: DNM1L

Hintergrund:

Background: Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. Through its function in mitochondrial division, ensures the survival of at least some types of postmitotic neurons, including Purkinje cells, by suppressing oxidative damage. Required for normal brain development, including that of cerebellum. Facilitates developmentally regulated apoptosis during neural tube formation. Required for a normal rate of cytochrome c release and caspase activation during apoptosis, this requirement may depend upon the cell type and the physiological apoptotic cues. Also required for mitochondrial fission during mitosis. Required for formation of endocytic vesicles. Proposed to regulate synaptic vesicle membrane dynamics through association with BCL2L1 isoform Bcl-X(L) which stimulates its GTPase activity in synaptic vesicles, the function may require its recruitment by MFF to clathrin-containing vesicles. Required for programmed necrosis execution.

Aliases: DLP1 antibody, dnm1l antibody, DNM1L_HUMAN antibody, Dnm1p/Vps1p-like protein antibody, dnml1 antibody, DRP1 antibody, DVLP antibody, Dymple antibody, Dynamin 1 like antibody, Dynamin family member proline-rich carboxyl-terminal domain less antibody, Dynamin like protein antibody, Dynamin related protein 1 antibody, Dynamin-1-like protein antibody, Dynamin-like protein 4 antibody, Dynamin-like protein antibody, Dynamin-like protein IV antibody, Dynamin-related protein 1 antibody, DYNIV 11 antibody, EMPF antibody, EMPF1 antibody, FLJ41912 antibody, HdynIV antibody, VPS1 antibody

UniProt: O00429