DSCAM Antikörper (AA 1711-1867) (HRP)

Produktnummer ABIN7150652

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DSCAM in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DSCAM Antikörper (AA 1711-1867) (HRP) (ABIN7150652)

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DSCAM Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-DSCAM Antikörper (HRP)

Bindungsspezifität: AA 1711-1867

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Down syndrome cell adhesion molecule protein (1711-1867AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DSCAM

Target: DSCAM (Down Syndrome Cell Adhesion Molecule (DSCAM))

Andere Bezeichnung: DSCAM

Hintergrund:

Background: Cell adhesion molecule that plays a role in neuronal self-avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self-avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies (PubMed:10925149). Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. In spinal chord development plays a role in guiding commissural axons projection and pathfinding across the ventral midline to reach the floor plate upon ligand binding (PubMed:18585357, PubMed:19196994). Enhances netrin-induced phosphorylation of PAK1 and FYN (PubMed:15169762). Mediates intracellular signaling by stimulating the activation of MAPK8 and MAP kinase p38 (PubMed:18585357, PubMed:19196994). Adhesion molecule that promotes lamina-specific synaptic connections in the retina: expressed in specific subsets of interneurons and retinal ganglion cells (RGCs) and promotes synaptic connectivity via homophilic interactions (By similarity).

Aliases: CHD2 42 antibody, CHD2 52 antibody, CHD2 antibody, Down syndrome cell adhesion molecule antibody, DSCAM antibody, DSCAM_HUMAN antibody, human CHD2-52 down syndrome cell adhesion molecule 2, 9 antibody, OTTHUMP00000109193 2 antibody, SD11109p antibody

UniProt: O60469

Pathways: Regulation of Cell Size