DOC2B Antikörper (AA 7-180)

Produktnummer ABIN7150615

Dieses Anti-DOC2B-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von DOC2B in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für DOC2B Antikörper (AA 7-180) (ABIN7150615)

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOC2B Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DOC2B Antikörper

Bindungsspezifität: AA 7-180

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DOC2B

Target: DOC2B (Double C2-Like Domains, beta (DOC2B))

Andere Bezeichnung: DOC2B

Hintergrund:

Background: Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes (By similarity).

Aliases: Doc2 beta antibody, Doc2-beta antibody, Doc2b antibody, DOC2B_HUMAN antibody, DOC2BL antibody, Double C2 like domain containing protein beta antibody, Double C2 like domains beta antibody, Double C2 like domains beta like antibody, Double C2-like domain-containing protein beta antibody, OTTMUSP00000006522 antibody, RP23 78H4.2 antibody

UniProt: Q14184

Pathways: Positive Regulation of Peptide Hormone Secretion