POLR2D Antikörper (AA 1-142)

Produktnummer ABIN7150434

Der Kaninchen Polyklonal Anti-POLR2D-Antikörper wurde für ELISA validiert. Er ist geeignet, POLR2D in Proben von Human zu detektieren.

Kurzübersicht für POLR2D Antikörper (AA 1-142) (ABIN7150434)

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POLR2D Antikörper ist unkonjugiert

Applikation: ELISA

Produktdetails anti-POLR2D Antikörper

Bindungsspezifität: AA 1-142

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed RNA polymerase II subunit RPB4 protein (1-142AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu POLR2D

Target: POLR2D (Polymerase (RNA) II (DNA Directed) Polypeptide D (POLR2D))

Andere Bezeichnung: POLR2D

Hintergrund:

Background: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB4 is part of a subcomplex with RPB7 that binds to a pocket formed by RPB1, RPB2 and RPB6 at the base of the clamp element. The RBP4-RPB7 subcomplex seems to lock the clamp via RPB7 in the closed conformation thus preventing double-stranded DNA to enter the active site cleft. The RPB4-RPB7 subcomplex binds single-stranded DNA and RNA.

Aliases: DNA directed RNA polymerase II 16 kDa polypeptide antibody, DNA directed RNA polymerase II subunit D antibody, DNA directed RNA polymerase II subunit RPB4 antibody, DNA-directed RNA polymerase II 16 kDa polypeptide antibody, DNA-directed RNA polymerase II subunit D antibody, DNA-directed RNA polymerase II subunit rpb4 antibody, HSRBP4 antibody, HSRPB4 antibody, polr2d antibody, polymerase RNA II DNA directed polypeptide D antibody, RBP4 antibody, RNA polymerase II 16 kDa subunit antibody, RNA polymerase II subunit B4 antibody, RNA polymerase II subunit D antibody, RNA polymerase II subunit hsRBP4 antibody, RPB16 antibody, RPB4_HUMAN antibody

UniProt: O15514

Pathways: Regulatorische RNA Pathways