CCDC111 Antikörper (AA 305-537)
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- Target Alle CCDC111 Antikörper anzeigen
- CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))
- Bindungsspezifität
- AA 305-537
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CCDC111 Antikörper ist unkonjugiert
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Applikation
- ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Kreuzreaktivität
- Human
- Aufreinigung
- >95%, Protein G purified
- Immunogen
- Recombinant Human DNA-directed primase/polymerase protein (305-537AA)
- Isotyp
- IgG
- Top Product
- Discover our top product CCDC111 Primärantikörper
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anti-Coiled-Coil Domain Containing 111 (CCDC111) antibody
CCDC111 Reaktivität: Human, Maus, Ratte IHC, IF, WB Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 - Konservierungsmittel
- ProClin
- Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C,-80 °C
- Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Target
- CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))
- Andere Bezeichnung
- PRIMPOL (CCDC111 Produkte)
- Synonyme
- BC065112 antikoerper, primase and DNA directed polymerase antikoerper, primase and polymerase (DNA-directed) antikoerper, PRIMPOL antikoerper, Primpol antikoerper
- Hintergrund
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Background: DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH.
Aliases: CC111_HUMAN antibody, CCDC111 antibody, Coiled coil domain containing 111 antibody, Coiled-coil domain-containing protein 111 antibody, DNA-directed primase/polymerase protein antibody, MYP22 antibody, Primase and polymerase (DNA directed) antibody, PRIMPOL antibody
- UniProt
- Q96LW4
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