CCDC111 Antikörper (AA 305-537)

Produktnummer ABIN7150406

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CCDC111 in ELISA, IHC und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CCDC111 Antikörper (AA 305-537) (ABIN7150406)

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCDC111 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CCDC111 Antikörper

Bindungsspezifität: AA 305-537

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human DNA-directed primase/polymerase protein (305-537AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCDC111

Target: CCDC111 (Coiled-Coil Domain Containing 111 (CCDC111))

Andere Bezeichnung: PRIMPOL

Hintergrund:

Background: DNA primase and DNA polymerase able to initiate de novo DNA synthesis using dNTPs. Shows a high capacity to tolerate DNA damage lesions such as 8oxoG and abasic sites in DNA. Involved in translesion synthesis via its primase activity by mediating uninterrupted fork progression after programmed or damage-induced fork arrest and by reinitiating DNA synthesis after dNTP depletion. Required for mitochondrial DNA (mtDNA) synthesis, suggesting it may be involved in DNA tolerance during the replication of mitochondrial DNA. Has non-overlapping function with POLH.

Aliases: CC111_HUMAN antibody, CCDC111 antibody, Coiled coil domain containing 111 antibody, Coiled-coil domain-containing protein 111 antibody, DNA-directed primase/polymerase protein antibody, MYP22 antibody, Primase and polymerase (DNA directed) antibody, PRIMPOL antibody

UniProt: Q96LW4