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MCM8 Antikörper (AA 1-67) (HRP)

This anti-MCM8 antibody (ABIN7150184) is a Rabbit Polyclonal antibody detecting MCM8 in ELISA. Suitable for Human.
Produktnummer ABIN7150184

Kurzübersicht für MCM8 Antikörper (AA 1-67) (HRP) (ABIN7150184)

Target

Alle MCM8 Antikörper anzeigen
MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

Reaktivität

  • 36
  • 11
  • 11
  • 6
  • 5
  • 4
  • 4
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Human

Wirt

  • 35
  • 1
Kaninchen

Klonalität

  • 35
  • 1
Polyklonal

Konjugat

  • 22
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Dieser MCM8 Antikörper ist konjugiert mit HRP

Applikation

  • 26
  • 17
  • 5
  • 1
  • 1
  • 1
ELISA
  • Bindungsspezifität

    • 8
    • 4
    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-67

    Kreuzreaktivität

    Human

    Aufreinigung

    >95%, Protein G purified

    Immunogen

    Recombinant Human DNA helicase MCM8 protein (1-67AA)

    Isotyp

    IgG
  • Applikationshinweise

    Optimal working dilution should be determined by the investigator.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

    Konservierungsmittel

    ProClin

    Vorsichtsmaßnahmen

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Lagerung

    -20 °C,-80 °C

    Informationen zur Lagerung

    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • Target

    MCM8 (Minichromosome Maintenance Deficient 8 (MCM8))

    Andere Bezeichnung

    MCM8

    Hintergrund

    Background: Component of the MCM8-MCM9 complex, a complex involved in homologous recombination repair following DNA interstrand cross-links and plays a key role during gametogenesis. The MCM8-MCM9 complex probably acts as a hexameric helicase downstream of the Fanconi anemia proteins BRCA2 and RAD51 and is required to process aberrant forks into homologous recombination substrates and to orchestrate homologous recombination with resection, fork stabilization and fork restart. May also play a non-essential for DNA replication: may be involved in the activation of the prereplicative complex (pre-RC) during G(1) phase by recruiting CDC6 to the origin recognition complex (ORC). Binds chromatin throughout the cell cycle.

    Aliases: C20orf154 antibody, dJ967N21.5 antibody, DNA helicase MCM8 antibody, DNA replication licensing factor MCM8 antibody, MCM8 antibody, MCM8_HUMAN antibody, MGC119522 antibody, MGC119523 antibody, MGC12866 antibody, MGC4816 antibody, Minichromosome maintenance 8 antibody, Minichromosome maintenance complex component 8 antibody, REC antibody

    UniProt

    Q9UJA3

    Pathways

    Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA
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