ADAM15 Antikörper (AA 207-452) (Biotin)

Produktnummer ABIN7150043

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch ADAM15 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für ADAM15 Antikörper (AA 207-452) (Biotin) (ABIN7150043)

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ADAM15 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-ADAM15 Antikörper (Biotin)

Bindungsspezifität: AA 207-452

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Disintegrin and metalloproteinase domain-containing protein 15 protein (207-452AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu ADAM15

Target: ADAM15 (ADAM Metallopeptidase Domain 15 (ADAM15))

Andere Bezeichnung: ADAM15

Hintergrund:

Background: Active metalloproteinase with gelatinolytic and collagenolytic activity. Plays a role in the wound healing process. Mediates both heterotypic intraepithelial cell/T-cell interactions and homotypic T-cell aggregation. Inhibits beta-1 integrin-mediated cell adhesion and migration of airway smooth muscle cells. Suppresses cell motility on or towards fibronectin possibly by driving alpha-v/beta-1 integrin (ITAGV-ITGB1) cell surface expression via ERK1/2 inactivation. Cleaves E-cadherin in response to growth factor deprivation. Plays a role in glomerular cell migration. Plays a role in pathological neovascularization. May play a role in cartilage remodeling. May be proteolytically processed, during sperm epididymal maturation and the acrosome reaction. May play a role in sperm-egg binding through its disintegrin domain.

Aliases: A disintegrin and metalloproteinase domain 15 (metargidin) antibody, A disintegrin and metalloproteinase domain 15 antibody, ADA15_HUMAN antibody, ADAM 15 antibody, ADAM metallopeptidase domain 15 antibody, Adam15 antibody, and cysteine-rich protein 15 antibody, Disintegrin and metalloproteinase domain-containing protein 15 antibody, disintegrin-like antibody, EC 3.4.24. antibody, MDC 15 antibody, MDC-15 antibody, MDC15 antibody, Metalloprotease RGD disintegrin protein antibody, Metalloproteinase like disintegrin like and cysteine rich protein 15 antibody, Metalloproteinase-like antibody, Metargidin antibody

UniProt: Q13444