DHRS2 Antikörper (AA 1-300)
Kurzübersicht für DHRS2 Antikörper (AA 1-300) (ABIN7149618)
Target
Alle DHRS2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-300
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Kreuzreaktivität
- Human
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Aufreinigung
- Antigen Affinity Purified
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Immunogen
- Recombinant Human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: IHC:1:20-1:200,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DHRS2 (Dehydrogenase/reductase (SDR Family) Member 2 (DHRS2))
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Andere Bezeichnung
- DHRS2
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Hintergrund
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Background: Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21.
Aliases: DHRS2 antibody, SDR25C1 antibody, Dehydrogenase/reductase SDR family member 2 antibody, mitochondrial antibody, EC 1.1.1.- antibody, Dicarbonyl reductase HEP27 antibody, Protein D antibody, Short chain dehydrogenase/reductase family 25C member 1 antibody
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UniProt
- Q13268
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Pathways
- C21-Steroid Hormone Metabolic Process
Target
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