DOCK7 Antikörper (AA 1440-1671) (Biotin)

Produktnummer ABIN7149600

Der Kaninchen Polyklonal Anti-DOCK7-Antikörper wurde für ELISA validiert. Er ist geeignet, DOCK7 in Proben von Human zu detektieren.

Kurzübersicht für DOCK7 Antikörper (AA 1440-1671) (Biotin) (ABIN7149600)

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DOCK7 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-DOCK7 Antikörper (Biotin)

Bindungsspezifität: AA 1440-1671

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Dedicator of cytokinesis protein 7 protein (1440-1671AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DOCK7

Target: DOCK7 (Dedicator of Cytokinesis 7 (DOCK7))

Andere Bezeichnung: DOCK7

Hintergrund:

Background: Functions as a guanine nucleotide exchange factor (GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 \\\'Ser-15\\\' phosphorylation during axon formation and consequently for neuronal polarization (PubMed:16982419). Has a role in pigmentation (By similarity). Involved in the regulation of cortical neurogenesis through the control of radial glial cells (RGCs) proliferation versus differentiation, negatively regulates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubule growth-promoting function of TACC3 (By similarity).

Aliases: DOCK7 antibody, KIAA1771Dedicator of cytokinesis protein 7 antibody

UniProt: Q96N67