DOCK3 Antikörper (AA 1630-1934) (FITC)
Kurzübersicht für DOCK3 Antikörper (AA 1630-1934) (FITC) (ABIN7149589)
Target
Alle DOCK3 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1630-1934
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Dedicator of cytokinesis protein 3 protein (1630-1934AA)
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Isotyp
- IgG
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anti-Dedicator of Cytokinesis 3 (DOCK3) (AA 1630-1934) antibody
DOCK3 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- DOCK3 (Dedicator of Cytokinesis 3 (DOCK3))
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Andere Bezeichnung
- DOCK3
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Hintergrund
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Background: Potential guanine nucleotide exchange factor (GEF). GEF proteins activate some small GTPases by exchanging bound GDP for free GTP. Its interaction with presenilin proteins as well as its ability to stimulate Tau/MAPT phosphorylation suggest that it may be involved in Alzheimer disease. Ectopic expression in nerve cells decreases the secretion of beta-amyloid APBA1 protein and lowers the rate of cell-substratum adhesion, suggesting that it may affect the function of some small GTPase involved in the regulation of actin cytoskeleton or cell adhesion receptors (By similarity).
Aliases: DOCK3 antibody, KIAA0299 antibody, MOCADedicator of cytokinesis protein 3 antibody, Modifier of cell adhesion antibody, Presenilin-binding protein antibody, PBP antibody
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UniProt
- Q8IZD9
Target
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