Nitrilase 1 Antikörper (AA 1-243)

Produktnummer ABIN7149534

Produktdetails anti-Nitrilase 1 Antikörper

Target: Nitrilase 1 (NIT1)

Bindungsspezifität: AA 1-243

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Nitrilase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Kreuzreaktivität: Human, Maus, Ratte

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Deaminated glutathione amidase protein (1-243AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Nitrilase 1

Target: Nitrilase 1 (NIT1)

Andere Bezeichnung: NIT1 (NIT1 Produkte)

Synonyme: MGC85476 antikoerper, zgc:101630 antikoerper, ZmNIT1 antikoerper, DDBDRAFT_0217173 antikoerper, DDBDRAFT_0302491 antikoerper, DDB_0217173 antikoerper, DDB_0302491 antikoerper, AI255805 antikoerper, ESTM30 antikoerper, W57327 antikoerper, A. THALIANA NITRILASE 1 antikoerper, ATNIT1 antikoerper, NITI antikoerper, NITRILE AMINOHYDROLASE antikoerper, nitrilase 1 antikoerper, nitrilase 1 S homeolog antikoerper, nitrilase 1 antikoerper, nit1.S antikoerper, nit1 antikoerper, NIT1 antikoerper, nit1-2 antikoerper, Nit1 antikoerper

Hintergrund:

Background: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.

Aliases: MGC57670 antibody, NIT1 antibody, NIT1_HUMAN antibody, Nitrilase 1 antibody, Nitrilase homolog 1 antibody

UniProt: Q86X76