Nitrilase 1 Antikörper (AA 1-243)
Kurzübersicht für Nitrilase 1 Antikörper (AA 1-243) (ABIN7149534)
Target
Alle Nitrilase 1 (NIT1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 1-243
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Kreuzreaktivität
- Human, Maus, Ratte
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Deaminated glutathione amidase protein (1-243AA)
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Isotyp
- IgG
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Applikationshinweise
- Recommended dilution: WB:1:500-1:5000, IHC:1:1000-1:2000, IF:1:200-1:500,
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- Nitrilase 1 (NIT1)
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Andere Bezeichnung
- NIT1
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Hintergrund
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Background: Catalyzes the hydrolysis of the amide bond in N-(4-oxoglutarate)-L-cysteinylglycine (deaminated glutathione), a metabolite repair reaction to dispose of the harmful deaminated glutathione. Plays a role in cell growth and apoptosis: loss of expression promotes cell growth, resistance to DNA damage stress and increased incidence to NMBA-induced tumors. Has tumor suppressor properties that enhances the apoptotic responsiveness in cancer cells, this effect is additive to the tumor suppressor activity of FHIT. It is also a negative regulator of primary T-cells.
Aliases: MGC57670 antibody, NIT1 antibody, NIT1_HUMAN antibody, Nitrilase 1 antibody, Nitrilase homolog 1 antibody
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UniProt
- Q86X76
Target
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