CIAO2A (AA 1-160) Antikörper (Biotin)

Produktnummer ABIN7149393

Der Kaninchen Polyklonal Anti--Antikörper wurde für ELISA validiert. Er ist geeignet, in Proben von Human zu detektieren.

Kurzübersicht für CIAO2A (AA 1-160) Antikörper (Biotin) (ABIN7149393)

Target: CIAO2A

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Biotin

Applikation: ELISA

Produktdetails

Bindungsspezifität: AA 1-160

Verwendungszweck: CIAO2A Antibody, Biotin conjugated

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human Cytosolic iron-sulfur assembly component 2A protein (1-160AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Antigendetails

Target: CIAO2A

Hintergrund:

Background: Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins (PubMed:23891004). As a CIA complex component and in collaboration with CIAO1 specifically matures ACO1 and stabilizes IREB2, connecting cytosolic iron-sulfur protein maturation with cellular iron regulation (PubMed:23891004). May play a role in chromosome segregation through establishment of sister chromatid cohesion. May induce apoptosis in collaboration with APAF1 (PubMed:25716227)

Aliases: CIAO2A antibody, CIA2A antibody, FAM96A antibody, Cytosolic iron-sulfur assembly component 2A antibody, MIP18 family protein FAM96A antibody

UniProt: Q9H5X1