CYFIP1 Antikörper (AA 320-449) (Biotin)

Produktnummer ABIN7149329

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CYFIP1 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CYFIP1 Antikörper (AA 320-449) (Biotin) (ABIN7149329)

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CYFIP1 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-CYFIP1 Antikörper (Biotin)

Bindungsspezifität: AA 320-449

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cytoplasmic FMR1-interacting protein 1 protein (320-449AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CYFIP1

Target: CYFIP1 (Cytoplasmic FMR1 Interacting Protein 1 (CYFIP1))

Andere Bezeichnung: CYFIP1

Hintergrund:

Background: Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (By similarity). May act as an invasion suppressor in cancers.

Aliases: CY antibody, CYFIP 1 antibody, CYFIP1 antibody, CYFP1_HUMAN antibody, Cytoplasmic FMR1 interacting protein 1 antibody, Cytoplasmic FMR1-interacting protein 1 antibody, FLJ45151 antibody, KIAA0068 antibody, p140sra 1 antibody, p140sra-1 antibody, P140SRA1 antibody, Selective hybridizing clone antibody, SHYC antibody, Specifically Rac1 associated protein 1 antibody, Specifically Rac1-associated protein 1 antibody, SRA 1 antibody, Sra-1 antibody, SRA1 antibody

UniProt: Q7L576