CDK13 Antikörper (AA 1-170) (HRP)

Produktnummer ABIN7148858

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CDK13 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CDK13 Antikörper (AA 1-170) (HRP) (ABIN7148858)

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDK13 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-CDK13 Antikörper (HRP)

Bindungsspezifität: AA 1-170

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cyclin-dependent kinase 13 protein (1-170AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CDK13

Target: CDK13 (Cyclin-Dependent Kinase 13 (CDK13))

Andere Bezeichnung: CDK13

Hintergrund:

Background: Cyclin-dependent kinase which displays CTD kinase activity and is required for RNA splicing. Has CTD kinase activity by hyperphosphorylating the C-terminal heptapeptide repeat domain (CTD) of the largest RNA polymerase II subunit RPB1, thereby acting as a key regulator of transcription elongation. Required for RNA splicing, probably by phosphorylating SRSF1/SF2. Required during hematopoiesis. In case of infection by HIV-1 virus, interacts with HIV-1 Tat protein acetylated at \'Lys-50\' and \'Lys-51\', thereby increasing HIV-1 mRNA splicing and promoting the production of the doubly spliced HIV-1 protein Nef.

Aliases: CDC2 related protein kinase 5 antibody, CDC2-related protein kinase 5 antibody, CDC2L antibody, CDK13 antibody, CDK13_HUMAN antibody, cell division controller cholinesterase related antibody, cell division cycle 2 like 5 (cholinesterase related cell division controller) antibody, cell division cycle 2 like 5 antibody, Cell division cycle 2 like protein kinase 5 antibody, Cell division cycle 2-like protein kinase 5 antibody, Cell division protein kinase 13 antibody, CHED antibody, Cholinesterase related cell division controller antibody, Cholinesterase-related cell division controller antibody, cyclin dependent kinase 13 antibody, Cyclin-dependent kinase 13 antibody, hCDK13 antibody

UniProt: Q14004