CNGA3 Antikörper (AA 1-165)

Produktnummer ABIN7148825

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNGA3 in ELISA und IHC. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNGA3 Antikörper (AA 1-165) (ABIN7148825)

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNGA3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CNGA3 Antikörper

Bindungsspezifität: AA 1-165

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Cyclic nucleotide-gated cation channel alpha-3 protein (1-165AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CNGA3

Target: CNGA3 (Cyclic Nucleotide Gated Channel alpha 3 (CNGA3))

Andere Bezeichnung: CNGA3

Hintergrund:

Background: Visual signal transduction is mediated by a G-protein coupled cascade using cGMP as second messenger. This protein can be activated by cyclic GMP which leads to an opening of the cation channel and thereby causing a depolarization of cone photoreceptors. Induced a flickering channel gating, weakened the outward rectification in the presence of extracellular calcium, increased sensitivity for L-cis diltiazem and enhanced the cAMP efficacy of the channel when coexpressed with CNGB3 (By similarity). Essential for the generation of light-evoked electrical responses in the red-, green- and blue sensitive cones.

Aliases: ACHM2 antibody, CCNC1 antibody, CCNCa antibody, CCNCalpha antibody, CNCG3 antibody, CNG 3 antibody, CNG channel alpha 3 antibody, CNG channel alpha-3 antibody, CNG-3 antibody, CNG3 antibody, CNGA3 antibody, Cnga3 cyclic nucleotide gated channel alpha 3 antibody, CNGA3_HUMAN antibody, Cone photoreceptor cGMP gated channel antibody, Cone photoreceptor cGMP gated channel alpha subunit antibody, Cone photoreceptor cGMP gated channel subunit alpha antibody, Cone photoreceptor cGMP-gated channel subunit alpha antibody, Cyclic nucleotide gated cation channel alpha 3 antibody, Cyclic nucleotide gated channel alpha 3 antibody, Cyclic nucleotide gated channel olfactory 3 antibody, Cyclic nucleotide gated channel rod photoreceptor subunit alpha antibody, Cyclic nucleotide-gated cation channel alpha-3 antibody, Cyclic nucleotide-gated channel alpha-3 antibody, OTTHUMP00000161120 antibody

UniProt: Q16281

Pathways: Phototransduction