CELF4 Antikörper (AA 120-236) (Biotin)

Produktnummer ABIN7148740

Dieses Anti-CELF4-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CELF4 in ELISA. Geeignet für Human.

Kurzübersicht für CELF4 Antikörper (AA 120-236) (Biotin) (ABIN7148740)

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CELF4 Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-CELF4 Antikörper (Biotin)

Bindungsspezifität: AA 120-236

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CUGBP Elav-like family member 4 protein (120-236AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CELF4

Target: CELF4 (CUGBP, Elav-Like Family Member 4 (CELF4))

Andere Bezeichnung: CELF4

Hintergrund:

Background: RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Promotes exclusion of both the smooth muscle (SM) and non-muscle (NM) exons in actinin pre-mRNAs. Activates the splicing of MAPT/Tau exon 10. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.

Aliases: CELF4 antibody, BRUNOL4 antibody, CUGBP Elav-like family member 4 antibody, CELF-4 antibody, Bruno-like protein 4 antibody, CUG-BP- and ETR-3-like factor 4 antibody, RNA-binding protein BRUNOL-4 antibody

UniProt: Q9BZC1

Pathways: Ribonucleoprotein Complex Subunit Organization, Synaptic Membrane