CNOT8 Antikörper (AA 1-292)

Produktnummer ABIN7147105

Dieses Anti-CNOT8-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CNOT8 in ELISA und IHC. Geeignet für Human.

Kurzübersicht für CNOT8 Antikörper (AA 1-292) (ABIN7147105)

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT8 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CNOT8 Antikörper

Bindungsspezifität: AA 1-292

Kreuzreaktivität: Human

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 8 protein (1-292AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CNOT8

Target: CNOT8 (CCR4-NOT Transcription Complex, Subunit 8 (CNOT8))

Andere Bezeichnung: CNOT8

Hintergrund:

Background: Has 3\\\'-5\\\' poly(A) exoribonuclease activity for synthetic poly(A) RNA substrate. Its function seems to be partially redundant with that of CNOT7. Catalytic component of the CCR4-NOT complex which is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. During miRNA-mediated repression the complex seems also to act as translational repressor during translational initiation. Additional complex functions may be a consequence of its influence on mRNA expression. Associates with members of the BTG family such as TOB1 and BTG2 and is required for their anti-proliferative activity.

Aliases: CAF 1 antibody, CAF 2 antibody, CAF1 antibody, CAF1 like protein antibody, CAF1-like protein antibody, CAF2 antibody, CALIF antibody, CALIFp antibody, CCR4 associated factor 8 antibody, CCR4 NOT transcription complex subunit 8 antibody, CCR4-associated factor 8 antibody, CCR4-NOT transcription complex subunit 8 antibody, CNOT 8 antibody, Cnot8 antibody, CNOT8_HUMAN antibody, hCAF1 antibody, PGK promoter directed over production antibody, POP 2 antibody, POP2 antibody

UniProt: Q9UFF9