CNOT2 Antikörper (AA 1-335) (HRP)

Produktnummer ABIN7147100

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CNOT2 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CNOT2 Antikörper (AA 1-335) (HRP) (ABIN7147100)

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CNOT2 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-CNOT2 Antikörper (HRP)

Bindungsspezifität: AA 1-335

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human CCR4-NOT transcription complex subunit 2 protein (1-335AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CNOT2

Target: CNOT2 (CCR4-NOT Transcription Complex, Subunit 2 (CNOT2))

Andere Bezeichnung: CNOT2

Hintergrund:

Background: Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Required for the CCR4-NOT complex structural integrity. Can repress transcription and may link the CCR4-NOT complex to transcriptional regulation, the repressive function may specificly involve the N-Cor repressor complex containing HDAC3, NCOR1 and NCOR2. Involved in the maintenance of emryonic stem (ES) cell identity.

Aliases: CCR4 associated factor 2 antibody, CCR4 NOT transcription complex subunit 2 antibody, CCR4-associated factor 2 antibody, CCR4-NOT transcription complex subunit 2 antibody, CDC36 antibody, CNOT2 antibody, CNOT2_HUMAN antibody, HSPC131 antibody, MSTP046 antibody, Negative regulator of transcription 2 antibody, NOT2 (negative regulator of transcription 2 yeast) homolog antibody, NOT2 antibody, NOT2H antibody

UniProt: Q9NZN8

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, Stem Cell Maintenance