CATSPER4 Antikörper (AA 306-472) (FITC)
Kurzübersicht für CATSPER4 Antikörper (AA 306-472) (FITC) (ABIN7147037)
Target
Alle CATSPER4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 306-472
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Kreuzreaktivität
- Human
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Aufreinigung
- >95%, Protein G purified
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Immunogen
- Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)
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Isotyp
- IgG
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anti-Cation Channel, Sperm Associated 4 (CATSPER4) (AA 306-472) antibody
CATSPER4 Reaktivität: Human ELISA, IHC, IF Wirt: Kaninchen Polyclonal unconjugated
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4 -
Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C,-80 °C
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Informationen zur Lagerung
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))
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Andere Bezeichnung
- CATSPER4
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Hintergrund
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Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .
Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody
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UniProt
- Q7RTX7
Target
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