CATSPER4 Antikörper (AA 306-472)

Produktnummer ABIN7147035

Der Kaninchen Polyklonal Anti-CATSPER4-Antikörper wurde für ELISA, IHC und IF validiert. Er ist geeignet, CATSPER4 in Proben von Human zu detektieren.

Kurzübersicht für CATSPER4 Antikörper (AA 306-472) (ABIN7147035)

Target: CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CATSPER4 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CATSPER4 Antikörper

Bindungsspezifität: AA 306-472

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Cation channel sperm-associated protein 4 protein (306-472AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CATSPER4

Target: CATSPER4 (Cation Channel, Sperm Associated 4 (CATSPER4))

Andere Bezeichnung: CATSPER4

Hintergrund:

Background: Voltage-gated calcium channel that plays a central role in calcium-dependent physiological responses essential for successful fertilization, such as sperm hyperactivation, acrosome reaction and chemotaxis towards the oocyte. Activated by extracellular progesterone and prostaglandins following the sequence: progesterone > PGF1-alpha = PGE1 > PGA1 > PGE2 >> PGD2. The primary effect of progesterone activation is to shift voltage dependence towards more physiological, negative membrane potentials, it is not mediated by metabotropic receptors and second messengers. Sperm capacitation enhances the effect of progesterone by providing additional negative shift. Also activated by the elevation of intracellular pH .

Aliases: CATSPER4Cation channel sperm-associated protein 4 antibody, CatSper4 antibody

UniProt: Q7RTX7