CASQ2 Antikörper (AA 219-300)

Produktnummer ABIN7146585

Der Kaninchen Polyklonal Anti-CASQ2-Antikörper wurde für WB, ELISA und IHC validiert. Er ist geeignet, CASQ2 in Proben von Human zu detektieren.

Kurzübersicht für CASQ2 Antikörper (AA 219-300) (ABIN7146585)

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CASQ2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Produktdetails anti-CASQ2 Antikörper

Bindungsspezifität: AA 219-300

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Calsequestrin-2 protein (219-300AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:500-1:5000, IHC:1:20-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CASQ2

Target: CASQ2 (Calsequestrin 2 (CASQ2))

Andere Bezeichnung: CASQ2

Hintergrund:

Background: Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2, this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

Aliases: AA033488 antibody, AW146219 antibody, Calsequestrin 2 (cardiac muscle) antibody, Calsequestrin 2 fast twitch cardiac muscle antibody, Calsequestrin antibody, Calsequestrin cardiac muscle isoform antibody, Calsequestrin fast twitch cardiac muscle antibody, Calsequestrin-2 antibody, Calsequestrin2 antibody, cardCSQ antibody, Cardiac calsequestrin 2 antibody, cardiac muscle isoform antibody, CASQ 2 antibody, CASQ2 antibody, CASQ2_HUMAN antibody, cCSQ antibody, ESTM52 antibody, FLJ26321 antibody, FLJ93514 antibody, PDIB2 antibody

UniProt: O14958

Pathways: Negative Regulation of Transporter Activity