CXCR4 Antikörper (AA 1-356) (HRP)

Produktnummer ABIN7146110

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch CXCR4 in ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für CXCR4 Antikörper (AA 1-356) (HRP) (ABIN7146110)

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CXCR4 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-CXCR4 Antikörper (HRP)

Bindungsspezifität: AA 1-356

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human C-X-C chemokine receptor type 4 protein (1-356AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CXCR4

Target: CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))

Andere Bezeichnung: CXCR4

Hintergrund:

Background: Receptor for the C-X-C chemokine CXCL12/SDF-1 that transduces a signal by increasing intracellular calcium ion levels and enhancing MAPK1/MAPK3 activation. Acts as a receptor for extracellular ubiquitin, leading to enhanced intracellular calcium ions and reduced cellular cAMP levels. Involved in hematopoiesis and in cardiac ventricular septum formation. Also plays an essential role in vascularization of the gastrointestinal tract, probably by regulating vascular branching and/or remodeling processes in endothelial cells. Involved in cerebellar development. In the CNS, could mediate hippocampal-neuron survival.

Aliases: C-X-C chemokine receptor type 4 antibody, CD184 antibody, CD184 antigen antibody, Chemokine (C X C motif) receptor 4 antibody, Chemokine CXC Motif Receptor 4 antibody, CXC-R4 antibody, CXCR-4 antibody, CXCR4 antibody, CXCR4_HUMAN antibody, D2S201E antibody, FB22 antibody, Fusin antibody, HM89 antibody, HSY3RR antibody, LAP 3 antibody, LAP3 antibody, LCR1 antibody, LESTR antibody, Leukocyte derived seven transmembrane domain receptor antibody, Leukocyte-derived seven transmembrane domain receptor antibody, Lipopolysaccharide associated protein 3 antibody, Neuropeptide Y receptor Y3 antibody, NPY3R antibody, NPYR antibody, NPYRL antibody, NPYY3 antibody, NPYY3R antibody, Probable G protein coupled receptor lcr1 homolog antibody, SDF 1 receptor antibody, SDF-1 receptor antibody, SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody, Stromal cell derived factor 1 receptor antibody, Stromal cell-derived factor 1 receptor antibody, WHIM antibody, WHIMS antibody

UniProt: P61073

Pathways: Regulation of Cell Size, CXCR4-mediated Signaling Events