CD207 Antikörper (AA 229-312)

Produktnummer ABIN7146085

Dieses Anti-CD207-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von CD207 in ELISA, IHC und IF. Geeignet für Human.

Kurzübersicht für CD207 Antikörper (AA 229-312) (ABIN7146085)

Target: CD207 (CD207 Molecule, Langerin (CD207))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CD207 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-CD207 Antikörper

Bindungsspezifität: AA 229-312

Verwendungszweck: CD207 Antibody

Aufreinigung: Protein G purified

Reinheit: >95 %

Immunogen: Recombinant Human C-type lectin domain family 4 member K protein (229-312AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CD207

Target: CD207 (CD207 Molecule, Langerin (CD207))

Andere Bezeichnung: CD207

Hintergrund:

Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs), is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Aliases: C type lectin domain family 4 member K antibody, C-type lectin domain family 4 member K antibody, CD 207 antibody, CD207 antibody, CD207 antigen antibody, CD207 antigen, langerin antibody, CD207 Molecule antibody, CLC4K_HUMAN antibody, CLEC 4K antibody, CLEC4K antibody, Langerhans cell specific c type lectin antibody, Langerin antibody, RGD1565913 antibody

UniProt: Q9UJ71