CCL5 Antikörper (AA 24-91) (HRP)

Produktnummer ABIN7146012

Der Kaninchen Polyklonal Anti-CCL5-Antikörper wurde für ELISA validiert. Er ist geeignet, CCL5 in Proben von Human zu detektieren.

Kurzübersicht für CCL5 Antikörper (AA 24-91) (HRP) (ABIN7146012)

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CCL5 Antikörper ist konjugiert mit HRP

Applikation: ELISA

Produktdetails anti-CCL5 Antikörper (HRP)

Bindungsspezifität: AA 24-91

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human C-C motif chemokine 5 protein (24-91AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu CCL5

Target: CCL5 (Chemokine (C-C Motif) Ligand 5 (CCL5))

Andere Bezeichnung: CCL5

Hintergrund:

Background: Chemoattractant for blood monocytes, memory T-helper cells and eosinophils. Causes the release of histamine from basophils and activates eosinophils. Binds to CCR1, CCR3, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant RANTES protein induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form RANTES(3-68) acts as a natural chemotaxis inhibitor and is a more potent inhibitor of HIV-1-infection. The second processed form RANTES(4-68) exhibits reduced chemotactic and HIV-suppressive activity compared with RANTES(1-68) and RANTES(3-68) and is generated by an unidentified enzyme associated with monocytes and neutrophils.

Aliases: Beta chemokine RANTES antibody, Beta chemokine RANTES precursor antibody, C C motif chemokine 5 antibody, CCL 5 antibody, CCL5 antibody, CCL5_HUMAN antibody, Chemokine (C C motif) ligand 5 antibody, Chemokine CC Motif Ligand 5 antibody, D17S136E antibody, EoCP antibody, Eosinophil chemotactic cytokine antibody, MGC17164 antibody, RANTES(4-68) antibody, Regulated upon activation normally T expressed and presumably secreted antibody, SCYA 5 antibody, SCYA5 antibody, SIS delta antibody, SIS-delta antibody, SISd antibody, Small inducible cytokine A5 (RANTES) antibody, Small inducible cytokine A5 antibody, Small inducible cytokine subfamily A (Cys Cys) member 5 antibody, Small-inducible cytokine A5 antibody, T cell specific protein p288 antibody, T cell specific protein RANTES antibody, T cell specific RANTES protein antibody, T cell-specific protein P228 antibody, T-cell-specific protein RANTES antibody, TCP 228 antibody, TCP228 antibody

UniProt: P13501

Pathways: Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, Smooth Muscle Cell Migration