BAG3 Antikörper (AA 220-420)

Produktnummer ABIN7145214

Der Kaninchen Polyklonal Anti-BAG3-Antikörper wurde für ELISA, IHC und IF validiert. Er ist geeignet, BAG3 in Proben von Human zu detektieren.

Kurzübersicht für BAG3 Antikörper (AA 220-420) (ABIN7145214)

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser BAG3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-BAG3 Antikörper

Bindungsspezifität: AA 220-420

Kreuzreaktivität: Human

Aufreinigung: >95%, Antigen Affinity purified & Affinity purified

Immunogen: Recombinant Human BAG family molecular chaperone regulator 3 protein (220-420AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu BAG3

Target: BAG3 (BCL2-Associated Athanogene 3 (BAG3))

Andere Bezeichnung: BAG3

Hintergrund:

Background: Co-chaperone for HSP70 and HSC70 chaperone proteins. Acts as a nucleotide-exchange factor (NEF) promoting the release of ADP from the HSP70 and HSC70 proteins thereby triggering client/substrate protein release. Nucleotide release is mediated via its binding to the nucleotide-binding domain (NBD) of HSPA8/HSC70 where as the substrate release is mediated via its binding to the substrate-binding domain (SBD) of HSPA8/HSC70 (PubMed:9873016, PubMed:27474739). Has anti-apoptotic activity (PubMed:10597216). Plays a role in the HSF1 nucleocytoplasmic transport (PubMed:26159920).

Aliases: BAG 3 antibody, BAG family molecular chaperone regulator 3 antibody, BAG-3 antibody, Bag3 antibody, BAG3_HUMAN antibody, Bcl 2 binding protein antibody, Bcl-2-associated athanogene 3 antibody, Bcl-2-binding protein Bis antibody, BCL2 associated athanogene 3 antibody, BCL2 binding athanogene 3 antibody, BIS antibody, CAIR 1 antibody, Docking protein CAIR 1 antibody, Docking protein CAIR-1 antibody, MFM6 antibody

UniProt: O95817