DHX36 Antikörper (AA 68-181)

Produktnummer ABIN7145003

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch DHX36 in ELISA und IF. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für DHX36 Antikörper (AA 68-181) (ABIN7145003)

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DHX36 Antikörper ist unkonjugiert

Applikation: ELISA, Immunofluorescence (IF)

Produktdetails anti-DHX36 Antikörper

Bindungsspezifität: AA 68-181

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human ATP-dependent RNA helicase DHX36 protein (68-181AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu DHX36

Target: DHX36 (DEAH (Asp-Glu-Ala-His) Box Polypeptide 36 (DHX36))

Andere Bezeichnung: DHX36

Hintergrund:

Background: Proposed to have a global role in regulating mRNA expression including transcriptional regulation and mRNA stability. Binds with high affinity to and resolves tetramolecular RNA and DNA quadruplex structures. Unwinds intramolecular quadruplexes derived from the ZIC1 and the MYC promoters. Binds to quadruplex structures in the promoters of YY1 and ALPL genes and regulates their expression. Binds to telomerase RNA template component (TERC) 5\'-end (nucleotides 1-43) and unwinds an internal quadruplex formation in TERC 5\'-end to promote P1 helix formation, the P1 helix acts as a template boundary ensuring accurate reverse transcription and is disrupted by quadruplex formation. May be involved in regulation of telomere length. Plays a role in degradation and deadenylation of mRNAs containing in their 3\'-UTR the consensus ARE sequence element. May function in sex development and spermatogenesis. May play a role in ossification.

Aliases: DDX36 antibody, DEAH box protein 36 antibody, Dhx36 antibody, DHX36_HUMAN antibody, EC 3.6.1.- antibody, KIAA1488 antibody, MLE like protein 1 antibody, MLE-like protein 1 antibody, MLEL1 antibody, Probable ATP dependent RNA helicase DHX36 antibody, Probable ATP-dependent RNA helicase DHX36 antibody, RHAU antibody, RNA helicase associated with AU rich element ARE antibody, RNA helicase associated with AU-rich element ARE antibody

UniProt: Q9H2U1

Pathways: Toll-Like Receptors Cascades