AHRR Antikörper (AA 255-506) (Biotin)

Produktnummer ABIN7144662

Der Kaninchen Polyklonal Anti-AHRR-Antikörper wurde für ELISA validiert. Er ist geeignet, AHRR in Proben von Human zu detektieren.

Kurzübersicht für AHRR Antikörper (AA 255-506) (Biotin) (ABIN7144662)

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHRR Antikörper ist konjugiert mit Biotin

Applikation: ELISA

Produktdetails anti-AHRR Antikörper (Biotin)

Bindungsspezifität: AA 255-506

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Aryl hydrocarbon receptor repressor protein (255-506AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Andere Bezeichnung: AHRR

Hintergrund:

Background: Mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.

Aliases: AHH antibody, AhR repressor antibody, AhRR antibody, AHRR_HUMAN antibody, aryl hydrocarbon hydroxylase regulator antibody, aryl hydrocarbon receptor regulator antibody, Aryl hydrocarbon receptor repressor antibody, Arylhydrocarbon receptor repressor antibody, bHLHe77 antibody, Class E basic helix-loop-helix protein 77 antibody, Dioxin receptor repressor antibody, KIAA1234 antibody, MGC167813 antibody, MGC176630 antibody, OTTHUMP00000221488 antibody, OTTHUMP00000221489 antibody

UniProt: A9YTQ3

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha