Aryl Hydrocarbon Receptor Antikörper (AA 126-353)

Produktnummer ABIN7144657

Dieses Anti-Aryl Hydrocarbon Receptor-Antikörper ist ein Kaninchen Polyklonal-Antikörper zur Detektion von Aryl Hydrocarbon Receptor in IHC, ELISA und IF. Geeignet für Human.

Kurzübersicht für Aryl Hydrocarbon Receptor Antikörper (AA 126-353) (ABIN7144657)

Target: Aryl Hydrocarbon Receptor (AHR)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Aryl Hydrocarbon Receptor Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Aryl Hydrocarbon Receptor Antikörper

Bindungsspezifität: AA 126-353

Kreuzreaktivität: Human

Aufreinigung: >95%, Protein G purified

Immunogen: Recombinant Human Aryl hydrocarbon receptor protein (126-353AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, PH 7.4

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu Aryl Hydrocarbon Receptor

Target: Aryl Hydrocarbon Receptor (AHR)

Andere Bezeichnung: AHR

Hintergrund:

Background: Ligand-activated transcriptional activator. Binds to the XRE promoter region of genes it activates. Activates the expression of multiple phase I and II xenobiotic chemical metabolizing enzyme genes (such as the CYP1A1 gene). Mediates biochemical and toxic effects of halogenated aromatic hydrocarbons. Involved in cell-cycle regulation. Likely to play an important role in the development and maturation of many tissues. Regulates the circadian clock by inhibiting the basal and circadian expression of the core circadian component PER1. Inhibits PER1 by repressing the CLOCK-ARNTL/BMAL1 heterodimer mediated transcriptional activation of PER1.

Aliases: Ah receptor antibody, AhR antibody, AHR_HUMAN antibody, Aromatic hydrocarbon receptor antibody, Aryl hydrocarbon receptor antibody, Aryl hydrocarbon receptor precursor antibody, bHLHe76 antibody, Class E basic helix loop helix protein 76 antibody, Class E basic helix-loop-helix protein 76 antibody, HGNC:348 antibody

UniProt: P35869

Pathways: Regulation of Cell Size