TP53BP2 Antikörper (AA 360-600)

Produktnummer ABIN7144484

Dieses Kaninchen Polyklonal-Antikörper erkennt spezifisch TP53BP2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für TP53BP2 Antikörper (AA 360-600) (ABIN7144484)

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TP53BP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-TP53BP2 Antikörper

Bindungsspezifität: AA 360-600

Kreuzreaktivität: Human, Maus

Aufreinigung: Antigen Affinity Purified

Immunogen: Recombinant Human Apoptosis-stimulating of p53 protein 2 protein (360-600AA)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Recommended dilution: WB:1:200-1:1000,

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,-80 °C

Informationen zur Lagerung: Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Details zu TP53BP2

Target: TP53BP2 (Tumor Protein P53 Binding Protein 2 (TP53BP2))

Andere Bezeichnung: TP53BP2

Hintergrund:

Background: Regulator that plays a central role in regulation of apoptosis and cell growth via its interactions. Regulates TP53 by enhancing the DNA binding and transactivation function of TP53 on the promoters of proapoptotic genes in vivo. Inhibits the ability of APPBP1 to conjugate NEDD8 to CUL1, and thereby decreases APPBP1 ability to induce apoptosis. Impedes cell cycle progression at G2/M. Its apoptosis-stimulating activity is inhibited by its interaction with DDX42.

Aliases: 53BP2 antibody, Apoptosis stimulating of p53 protein 2 antibody, Apoptosis stimulating protein of p53 2 antibody, Apoptosis-stimulating of p53 protein 2 antibody, ASPP2 antibody, ASPP2_HUMAN antibody, BBP antibody, Bcl2 binding protein antibody, Bcl2-binding protein antibody, NY REN 51 antigen antibody, p53 binding protein 2 antibody, p53-binding protein 2 antibody, p53BP2 antibody, PPP1R13A antibody, Renal carcinoma antigen NY-REN-51 antibody, Tp53bp2 antibody, Tumor protein p53 binding protein 2 antibody, Tumor suppressor p53 binding protein 2 antibody, Tumor suppressor p53-binding protein 2 antibody

UniProt: Q13625